The halves of two bodies, one belonging to a female Swedish politician, are discovered in the middle of the Øresund Bridge, which connects Copenhagen in Denmark with Malmö in Sweden. The body, cut in half at the waist, has been placed precisely on the border between the countries, thus falling under the jurisdiction of both the Danish and Swedish police agencies. After further examination, it turns out that the body is that of two separate corpses, with one half belonging to a Danish prostitute. Saga Norén, from the Swedish side, and Martin Rohde, from the Danish, lead the investigation to catch the murderer.[4][5]　　The investigation quickly escalates as a journalist, Daniel Ferbé, whose car was used in the crime, begins receiving phone calls. The caller, who becomes known as the "Truth Terrorist", claims to be committing his crimes in order to draw attention to various social problems. A social worker, Stefan Lindberg, whose sister becomes a victim of the Truth Terrorist, becomes an early suspect. However, events soon lead the Danish and Swedish teams to conclude that the killer has connections to the police. They discover that the crimes have been planned over a period of several years. The trail eventually leads them to Jens, a Danish policeman and former close friend of Martin's, who was thought to have committed suicide after an accident on the bridge caused the deaths of his wife and son.　　In the course of the investigation, Martin and Saga develop a close working relationship, although they are very different people. Martin has a twenty-year old son from his first marriage, August, who is now living with Martin and his current wife, Mette, by whom Martin has three children; after Martin has had a vasectomy, Mette discovers that she is expecting twins. Saga lives alone and does not seem to feel she needs a serious relationship, instead picking up men in bars for casual sex. She appears to have symptoms consistent with Asperger syndrome, resulting in difficulty establishing relationships and feelings of inadequacy in managing people; she refuses a promotion for this latter reason.　　After the killer has murdered several people and successfully thrown red herrings in the way of the investigation, his true purpose - to strike at Martin himself - eventually becomes clear. Jens, now calling himself Sebastian Sandstrod, first approaches Mette, who is susceptible to his advances, after learning that Martin has slept with Charlotte Söringer, a woman who is peripherally involved in the investigation. Sebastian lures Mette and her children to a remote spot where he subjects them to a terrifying ordeal, locking them in with a room and giving her a hand grenade with its pin removed to hold as long as she can. However, Saga realises that August is the real target. The investigation culminates in a confrontation on the bridge, where she cannot help but tell Martin what happened to August and has to fire at him in order to prevent him destroying his career by killing Sebastian, the killer's final intention.

　　夜幕笼罩下的肯尼迪国际机场，一架从柏林飞来的航班悄无声息降落在废弃的跑道上。蹊跷的事件引来各部门的关注，美国疾控中心纽约地区首席医疗官伊弗雷姆·古德温泽（寇瑞·斯托尔 Corey Stoll 饰）带领部下进入机舱，发现两百多名乘客在毫无知觉的情况下神秘死亡。从未见过的寄生虫、突然复活的死者、离奇消失的巨型棺材以及官方语焉不详欲盖弥彰的说辞，全部为这起事件蒙上了诡异而危险的面纱。犹太老人亚伯拉罕·赛特拉基安（大卫·布莱德利 David Bradley 饰）的警告历历在耳，接二连三的凶杀则将伊弗引向未知的方向。　　是异种入侵？或是神秘病毒蔓延？抑或是古老传说中的吸血鬼？前途扑朔迷离……